Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

The epitope recognized by PLA0202 maps to a region between residue 437 and 487 of human activating transcription factor 2 using the numbering given in entry AAY17203.1 (GeneID 1386).

Other Notes

Activating transcription factor 2 (ATF2) is a leucine-zipper transcription factor that binds to the cAMP-responsive element (CRE). ATF2 is involved in regulating the expression of a variety of proteins that are important to oncogenesis. It is a substrate of the JNK/p38 and ATM/ATR protein kinases which regulate its transactivating activity in response to environmental signals.

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide